ThinkitDrinkit's Bone Support BOOST is formulated from ingredients that are proven to provide significant bone-building benefits for people whose bones are weakened by aging or wear-and-tear related to athletic activity.
Calcium, vitamin D, and other important bone-building cofactors are essential to provide adequate nutrition for the ongoing process of bone remodeling.
Calcium is critical for healthy bone structure and density, as well as proper cell function and metabolism. It is the most abundant mineral element in the body by mass(1). Calcium is the structural foundation in the bone tissue, essential for bone rigidity and solidity playing an important role in building stronger, denser bones early in life, and keeping bones strong and healthy later in life. Ninety-nine percent of total calcium constitutes the skeleton and the teeth
ISALTIS (2015.) Calcium. Retrieved from http://www.isaltis.com/en/module/99999689/7/givocal_#!/en/module/99999688/1/calcium
Vitamin D helps calcium absorption needed for strong bone health as it assists the parathyroid hormone in bone formation. The complex process of vitamin D synthesis and utilization yields the active form, calcitriol, a hormone-like compound essential to cellular proliferation and rejuvenation. It is able to activate over 2,000 genes (roughly 10% of the human genome). While human skin cells can manufacture vitamin D from UV sunlight, lifestyle changes mean we spend more time indoors, and many people lack adequate sun exposure(1). Additionally, vitamin D is integral to a variety of physiological functions, and while it is manufactured by the skin, it is distributed throughout the body and not stored at the source.
Pediatric Orthopaedic Society of North America (2011, October) Vitamin D for Good Bone Health. Retrieved from http://orthoinfo.aaos.org/topic.cfm?topic=a00567
Magnesium supports calcium absorption and Vitamin D metabolism for improved bone density. Magnesium is involved in the formation of bone, regulating the concentrations of parathyroid hormone and vitamin D, which are major regulators of bone remodeling, a constant process of releasing and storing calcium. Several population-based studies have found positive associations between magnesium intake and bone mineral density in both men and women(1). Additional studies have shown that blood magnesium levels are lower in women with osteoporosis than those with osteopenia whose levels are in turn, lower than women with normal bone density(2). These results suggest that a magnesium deficiency may be a risk factor for the development of osteoporosis.
Magnesium. (n.d.). Retrieved January 28, 2015, from http://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/
Mutlu, M., Argun, M., Kilic, E., Saraymen, R., & Yazar, S. (2007). Magnesium, zinc and copper status in osteoporotic, osteopenic and normal post-menopausal women. The Journal of International Medical Research, 35(5), 692-695.
Vitamin K2 aids in building stronger bones and improving bone mineral density by removing excess calcium from arteries. Vitamin K2 is also associated with lower levels of circulating inactive osteocalcin. Osteocalcin is a vitamin-K dependent protein and is necessary for the body to utilize calcium in bone tissue. If there is insufficient vitamin K in bone tissue, the osteocalcin remains inactive(1).
Daniels, S. (2013, March 27) Vitamin K2 shows ‘extremely important improvements in clinical outcomes’ for bone health. Retrieved from http://www.nutraingredients-usa.com/Research/Vitamin-K2-shows-extremely-important-improvements-in-clinical-outcomes-for-bone-health
Boron plays an integral part in bone metabolism, as it supports the functions of calcium, magnesium, and vitamin D, all of which are crucial to promoting dense, healthy bone tissue(1). As a trace mineral, boron is needed in smaller amounts than calcium or magnesium, but is nevertheless very important for optimal bone health. In a study of postmenopausal women the subjects consumed a boron-deficient diet for 119 days, followed by 48 days of boron supplementation. When on the boron-depletion diet, the women demonstrated increased urinary loss of both calcium and magnesium. On the boron-supplemented diet, however, they showed less urinary excretion of calcium and magnesium, as well as increased levels of two hormones associated with healthy bone mass(2).
Miggiano, G.A., Gagliardi, L. (2005) Diet, nutrition and bone health. La Clinica terapeutica, 156(1-2):47-56.
Nielsen, F.H., Hunt, C.D., Mullen, L.M., Hunt, J.R.. (1987) Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women. FASEB Journal.1(5):394-7
Learn more about the benefits of GIVOCAL on the manufacturer's website.
The products and information found on this website are not intended to replace professional medical advice or treatment. Statements and claims have not been evaluated by the Food and Drug Administration. Our dietary supplements are not intended to diagnose, treat, cure or prevent any disease or medical condition. Individual results may vary.
ThinkitDrinkit urges you to seek the advice of a qualified professional for any health concern lasting more than two weeks, and to share with your provider any information pertaining to your health and well-being, including the use of supplemental nutrition.
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